![]() demonstrated that the procedure of ex vivo expansion of autologous Mesenchymal Stem Cells (MSCs) and transplantation into the spinal cord of humans was safe and well tolerated by ALS patients. Stem Cell-based therapies may be the answer. ALS is not a typical autoimmune disorder, since autoimmune and inflammatory abnormalities are not the cause of the disease, even though they influence its progression. Often, the origin of the disease is unknown. This results in a severe motor dysfunction muscles become atrophic due to the lack of nerve stimulation. It is a complex disease which involves the activation of several cellular pathways in both neurons and glial cells.
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